<p>After oral administration, about 95% of naproxen and it's metabolites can be recovered in the urine with 66-92% recovered as conjugated metabolite and less than 1% recovered as naproxen or desmethylnaproxen.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Falany CN, Strom P, Swedmark S: Sulphation of o-desmethylnaproxen and related compounds by human cytosolic sulfotransferases. Br J Clin Pharmacol. 2005 Dec;60(6):632-40. doi: 10.1111/j.1365-2125.2005.02506.x. (PubMed ID 16305588)" href="#reference-A179197">7</a></sup><sup class="text-reference-group"><a class="reference-popover-link" data-content="Naprelan FDA Label" href="#reference-L6582">12</a></sup><sup class="text-reference-group"><a class="reference-popover-link" data-content="Naprosyn FDA Label" href="#reference-L6583">13</a></sup> Less than 5% of naproxen is excreted in the feces.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Naprelan FDA Label" href="#reference-L6582">12</a></sup><sup class="text-reference-group"><a class="reference-popover-link" data-content="Naprosyn FDA Label" href="#reference-L6583">13</a></sup></p>