<p>The half life of minocycline pellet filled capsules is 11.1-22.1 hours.<sup class="text-reference-group"><a class="reference-popover-link" data-content="FDA Approved Drug Products: Minocin Minocycline Oral Pellet-Filled Capsules" href="#reference-L11710">13</a></sup> Minocycline intravenous injections have a half live of 15-23 hours.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Simon C, Malerczyk V, Preuss I, Schmidt K, Grahmann H: [Activity in vitro and pharmacokinetics of minocycline (author's transl)]. Arzneimittelforschung. 1976 Apr;26(4):556-60. (PubMed ID 782466)" href="#reference-A190702">4</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: Minocin Minocycline Powder for Intravenous Injection" href="#reference-L11713">14</a></sup></p>