<p>Minocycline is 76% protein bound in serum.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Zhou J, Tran BT, Tam VH: The complexity of minocycline serum protein binding. J Antimicrob Chemother. 2017 Jun 1;72(6):1632-1634. doi: 10.1093/jac/dkx039. (PubMed ID 28333250)" href="#reference-A190714">6</a></sup></p>