<p>The protein binding of amiodarone is about 96%.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Latini R, Tognoni G, Kates RE: Clinical pharmacokinetics of amiodarone. Clin Pharmacokinet. 1984 Mar-Apr;9(2):136-56. doi: 10.2165/00003088-198409020-00002. (PubMed ID 6370540)" href="#reference-A36817">4</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: CORDARONE (amiodarone HCl) tablets" href="#reference-L3561">18</a></sup></p>