<p>Minocycline is primarily metabolized to 9-hydroxyminocycline.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Nelis HJ, De Leenheer AP: Metabolism of minocycline in humans. Drug Metab Dispos. 1982 Mar-Apr;10(2):142-6. (PubMed ID 6124399)" href="#reference-A190696">2</a></sup> It is also metabolized to 2 different N-demethylated metabolites.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Nelis HJ, De Leenheer AP: Metabolism of minocycline in humans. Drug Metab Dispos. 1982 Mar-Apr;10(2):142-6. (PubMed ID 6124399)" href="#reference-A190696">2</a></sup></p><p class="d-none d-sm-block"><strong>Hover over products below to view reaction partners</strong></p>