<p>The oral LD<sub>50</sub> in rats is 2380mg/kg and in mice is 3600mg/kg.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Cayman Chemical: Minocycline MSDS" href="#reference-L11722">17</a></sup> The intraperitoneal LD<sub>50</sub> in rats is 331mg/kg and in mice is 299mg/kg.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Cayman Chemical: Minocycline MSDS" href="#reference-L11722">17</a></sup> The subcutaneous LD<sub>50</sub> in rats is 1700mg/kg and in mice is 2290mg/kg.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Cayman Chemical: Minocycline MSDS" href="#reference-L11722">17</a></sup></p><p>Patients experiencing an overdose may present with dizziness, nausea, and vomiting.<sup class="text-reference-group"><a class="reference-popover-link" data-content="FDA Approved Drug Products: Minocin Minocycline Oral Pellet-Filled Capsules" href="#reference-L11710">13</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: Minocin Minocycline Powder for Intravenous Injection" href="#reference-L11713">14</a></sup> In the event of an overdose, discontinue minocycline and treat patients with symptomatic and supportive measures.<sup class="text-reference-group"><a class="reference-popover-link" data-content="FDA Approved Drug Products: Ximino Minocycline Oral Extended Release Capsules" href="#reference-L11701">10</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: Solodyn Minocycline Oral Extended Release Tablets" href="#reference-L11704">11</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: Minocycline Oral Capsules" href="#reference-L11707">12</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: Minocin Minocycline Oral Pellet-Filled Capsules" href="#reference-L11710">13</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: Minocin Minocycline Powder for Intravenous Injection" href="#reference-L11713">14</a></sup></p>