<p>Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Latini R, Tognoni G, Kates RE: Clinical pharmacokinetics of amiodarone. Clin Pharmacokinet. 1984 Mar-Apr;9(2):136-56. doi: 10.2165/00003088-198409020-00002. (PubMed ID 6370540)" href="#reference-A36817">4</a></sup> Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved for its approved indications, according to prescribing information.<sup class="text-reference-group"><a class="reference-popover-link" data-content="FDA Approved Drug Products: CORDARONE (amiodarone HCl) tablets" href="#reference-L3561">18</a>,<a class="reference-popover-link" data-content="NIH StatPearls: Amiodarone" href="#reference-L11265">19</a>,<a class="reference-popover-link" data-content="AAFP: Medication Guide for Amiodarone" href="#reference-L11286">20</a></sup></p>