<p>Nifedipine is 92-98% protein bound in serum.<sup class="text-reference-group"><a class="reference-popover-link" data-content="FDA Approved Drug Products: Procardia Nifedipine Oral Capsules" href="#reference-L11383">13</a></sup> Nifedipine is 97±12% bound in a 40g/L solution of pure albumin.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Otto J, Lesko LJ: Protein binding of nifedipine. J Pharm Pharmacol. 1986 May;38(5):399-400. doi: 10.1111/j.2042-7158.1986.tb04598.x. (PubMed ID 2872322)" href="#reference-A190207">2</a></sup> Nifedipine is 51.4±5.9% protein bound in a 50mg/100mL solution of alpha-1-acid glycoprotein, and 75.5±3.5% protein bound in a 150mg/mL solution.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Otto J, Lesko LJ: Protein binding of nifedipine. J Pharm Pharmacol. 1986 May;38(5):399-400. doi: 10.1111/j.2042-7158.1986.tb04598.x. (PubMed ID 2872322)" href="#reference-A190207">2</a></sup></p>