<p>Naproxen is highly protein bound with &gt;99% of the drug bound to albumin at therapeutic levels.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Naprelan FDA Label" href="#reference-L6582">12</a></sup><sup class="text-reference-group"><a class="reference-popover-link" data-content="Naprosyn FDA Label" href="#reference-L6583">13</a></sup></p>