<p>The volume of distribution of minocycline has been reported as 67.5-115L.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Saivin S, Houin G: Clinical pharmacokinetics of doxycycline and minocycline. Clin Pharmacokinet. 1988 Dec;15(6):355-66. doi: 10.2165/00003088-198815060-00001. (PubMed ID 3072140)" href="#reference-A190708">5</a></sup></p>