<p>Progesterone metabolites are excreted mainly by the kidneys. Urinary elimination is observed for 95% of patients in the form of glycuroconjugated metabolites, primarily 3 a, 5 ß–pregnanediol (<em>pregnandiol</em>) <sup class="text-reference-group"><a class="reference-popover-link" data-content="Utrogestan capsules, medsafe NZ label" href="#reference-F3913">24</a></sup>. The glucuronide and sulfate conjugates of pregnanediol and pregnanolone are excreted in the urine and bile. Progesterone metabolites, excreted in the bile, may undergo enterohepatic recycling or may be found excreted in the feces. </p>