<p>Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Furosemide - FDA Label" href="#reference-L7958">9</a></sup> Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Furosemide - StatPearls - NCBI Bookshelf" href="#reference-L7961">10</a></sup> It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Prandota J: Clinical pharmacology of furosemide in children: a supplement. Am J Ther. 2001 Jul-Aug;8(4):275-89. (PubMed ID 11441327)" href="#reference-A182495">1</a></sup> The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Furosemide - FDA Label" href="#reference-L7958">9</a></sup></p>