<p>T<sub>4</sub> half-life is 6 to 7 days. T<sub>3</sub> half-life is 1 to 2 days.<sup class="text-reference-group"><a class="reference-popover-link" data-content="American Association of Clinical Endocrinologists (AACE): Clinical Practice Guidelines for Hypothyroidism in Adults" href="#reference-F4636">15</a></sup></p>