Every time it rains, fish living downstream of storm drains are exposed to pollutants, including the tire-derived compound 6PPD-quinone, in the runoff. Recently, this substance has been linked to massive die-offs of coho salmon across the U.S. West Coast. Now, researchers report that exposure to 6PPD-quinone at environmentally relevant levels can also be deadly for rainbow and brook trout, though not for Arctic char or white sturgeon.