<p>Erythromycin demonstrates 93% serum protein binding in the erythromycin propionate form.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Gordon RC, Regamey C, Kirby WM: Serum protein binding of erythromycin, lincomycin, and clindamycin. J Pharm Sci. 1973 Jul;62(7):1074-7. (PubMed ID 4714113)" href="#reference-A174454">7</a></sup> Another resource indicates that erythromycin protein binding ranges from 80 to 90%.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Periti P, Mazzei T, Mini E, Novelli A: Clinical pharmacokinetic properties of the macrolide antibiotics. Effects of age and various pathophysiological states (Part I). Clin Pharmacokinet. 1989 Apr;16(4):193-214. doi: 10.2165/00003088-198916040-00001. (PubMed ID 2656049)" href="#reference-A33081">18</a></sup></p>