<p>Carbamazepine is 75%-80% bound to plasma proteins.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Tolou-Ghamari Z, Zare M, Habibabadi JM, Najafi MR: A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012. J Res Med Sci. 2013 Mar;18(Suppl 1):S81-5. (PubMed ID 23961295)" href="#reference-A180301">3</a>,<a class="reference-popover-link" data-content="FDA Approved Drug Products: EQUETRO (carbamazepine) extended-release capsules" href="#reference-L1335">16</a></sup> One pharmacokinetic study indicates that it is 72% bound to plasma proteins.<sup class="text-reference-group"><a class="reference-popover-link" data-content="Rawlins MD, Collste P, Bertilsson L, Palmer L: Distribution and elimination kinetics of carbamazepine in man. Eur J Clin Pharmacol. 1975 Feb 28;8(2):91-6. (PubMed ID 1233212)" href="#reference-A180424">11</a></sup></p>