<dl class="inner-dl"><dt class="col-md-4 col-sm-5" id="description">Description</dt><dd class="col-md-8 col-sm-7">This compound belongs to the class of organic compounds known as podophyllotoxins. These are tetralin lignans in which the benzene moiety of the tetralin skeleton is fused to a 1,3-dioxolane and the cyclohexane is fused to a butyrolactone (pyrrolidin-2-one).</dd><dt class="col-md-4 col-sm-5" id="kingdom">Kingdom</dt><dd class="col-md-8 col-sm-7"><a class="classyfire-taxnode" data-content="Compounds that contain at least one carbon atom, excluding isocyanide/cyanide and their non-hydrocarbyl derivatives, thiophosgene, carbon diselenide, carbon monosulfide, carbon disulfide, carbon subsulfide, carbon monoxide, carbon dioxide, Carbon suboxide, and dicarbon monoxide." href="http://classyfire.wishartlab.com/tax_nodes/C0000000" rel="noopener" target="_blank">Organic compounds</a></dd><dt class="col-md-4 col-sm-5" id="super-class">Super Class</dt><dd class="col-md-8 col-sm-7"><a class="classyfire-taxnode" data-content="Plant products of low molecular weight formed primarily from oxidative coupling of two p-propylphenol moieties. They can also be described as micromolecules with two phenylpropanoid units coupled together. They can be attached in various manners, like C5-C5', C8-C8'. Most known natural lignans are oxidized at C9 and C9´ and, based upon the way in which oxygen is incorporated into the skeleton and on the cyclization patterns, a wide range of lignans of very different structural types can be formed." href="http://classyfire.wishartlab.com/tax_nodes/C0001392" rel="noopener" target="_blank">Lignans, neolignans and related compounds</a></dd><dt class="col-md-4 col-sm-5" id="class">Class</dt><dd class="col-md-8 col-sm-7"><a class="classyfire-taxnode" data-content="Lignans that contain a lactone moiety. They include 1-aryltetralin lactones, dibenzylbutyrolactone lignans, and podophyllotoxins, among others." href="http://classyfire.wishartlab.com/tax_nodes/C0001510" rel="noopener" target="_blank">Lignan lactones</a></dd><dt class="col-md-4 col-sm-5" id="sub-class">Sub Class</dt><dd class="col-md-8 col-sm-7"><a class="classyfire-taxnode" data-content="Tetralin lignans in which the benzene moiety of the tetralin skeleton is fused to a 1,3-dioxolane and the cyclohexane is fused to a butyrolactone (pyrrolidin-2-one)." href="http://classyfire.wishartlab.com/tax_nodes/C0000047" rel="noopener" target="_blank">Podophyllotoxins</a></dd><dt class="col-md-4 col-sm-5" id="direct-parent">Direct Parent</dt><dd class="col-md-8 col-sm-7"><a class="classyfire-taxnode" data-content="Tetralin lignans in which the benzene moiety of the tetralin skeleton is fused to a 1,3-dioxolane and the cyclohexane is fused to a butyrolactone (pyrrolidin-2-one)." href="http://classyfire.wishartlab.com/tax_nodes/C0000047" rel="noopener" target="_blank">Podophyllotoxins</a></dd><dt class="col-md-4 col-sm-5" id="alternative-parents">Alternative Parents</dt><dd class="col-md-8 col-sm-7"><span class="separated-list-container"><span class="separated-list col-lg-12 col-xl-6"><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Lignans with a structure based on the 1-phenyltetralin skeleton." href="http://classyfire.wishartlab.com/tax_nodes/C0003425" rel="noopener" target="_blank">Aryltetralin lignans</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Aromatic heterocyclic compounds containing a 1,3-dioxole ring linearly fused to the a naphthofuran." href="http://classyfire.wishartlab.com/tax_nodes/C0004792" rel="noopener" target="_blank">Furanonaphthodioxoles</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Polycyclic aromatic compounds containing a tetralin moiety, which consists of a benzene fused to a cyclohexane." href="http://classyfire.wishartlab.com/tax_nodes/C0000048" rel="noopener" target="_blank">Tetralins</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Polycyclic compounds containing a pyranodioxin moiety, which consists of a pyran ring fused to a dioxin ring." href="http://classyfire.wishartlab.com/tax_nodes/C0002011" rel="noopener" target="_blank">Pyranodioxins</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic aromatic compounds containing a monocyclic benzene moiety carrying exactly two methoxy groups." href="http://classyfire.wishartlab.com/tax_nodes/C0004111" rel="noopener" target="_blank">Dimethoxybenzenes</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Compounds containing a methoxy group attached to the benzene ring of a phenol moiety." href="http://classyfire.wishartlab.com/tax_nodes/C0000190" rel="noopener" target="_blank">Methoxyphenols</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic compounds containing a benzene ring fused to either isomers of dioxole. Dioxole is a five-membered unsaturated ring of two oxygen atoms and three carbon atoms." href="http://classyfire.wishartlab.com/tax_nodes/C0000296" rel="noopener" target="_blank">Benzodioxoles</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic compounds containing a methoxybenzene or a derivative thereof." href="http://classyfire.wishartlab.com/tax_nodes/C0000138" rel="noopener" target="_blank">Anisoles</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Aromatic compounds contaning a phenoxy group." href="http://classyfire.wishartlab.com/tax_nodes/C0004742" rel="noopener" target="_blank">Phenoxy compounds</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic compounds containing the alkyl aryl ether functional group with the generic formula R-O-R' , where R is an alkyl group and R' is an aryl group." href="http://classyfire.wishartlab.com/tax_nodes/C0000128" rel="noopener" target="_blank">Alkyl aryl ethers</a></span></span></span><span class="hidden-taxonomy" style="display: none"><span class="list-separator"> / </span><span class="separated-list-container"><span class="separated-list col-lg-12 col-xl-6"><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic compounds containing 1,3-dioxane, an aliphatic six-member ring with two oxygen atoms in ring positions 1 and 3." href="http://classyfire.wishartlab.com/tax_nodes/C0001314" rel="noopener" target="_blank">1,3-dioxanes</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Compounds containing an oxane (tetrahydropyran) ring, which is a six-member saturated aliphatic heterocycle with one oxygen atom and five carbon atoms." href="http://classyfire.wishartlab.com/tax_nodes/C0002012" rel="noopener" target="_blank">Oxanes</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Compounds containing one carbohydrate unit not glycosidically linked to another such unit, and no set of two or more glycosidically linked carbohydrate units. Monosaccharides have the general formula CnH2nOn." href="http://classyfire.wishartlab.com/tax_nodes/C0001540" rel="noopener" target="_blank">Monosaccharides</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom." href="http://classyfire.wishartlab.com/tax_nodes/C0001245" rel="noopener" target="_blank">Gamma butyrolactones</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Heterocyclic compounds containing a saturated, aliphatic, five-membered ring where a carbon is replaced by an oxygen." href="http://classyfire.wishartlab.com/tax_nodes/C0002648" rel="noopener" target="_blank">Tetrahydrofurans</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Carboxylic acid derivatives in which the carbon atom from the carbonyl group is attached to an alkyl or an aryl moiety through an oxygen atom (forming an ester group)." href="http://classyfire.wishartlab.com/tax_nodes/C0001238" rel="noopener" target="_blank">Carboxylic acid esters</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Polyols containing an alcohol group at two adjacent positions." href="http://classyfire.wishartlab.com/tax_nodes/C0002467" rel="noopener" target="_blank">1,2-diols</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Compounds containing a secondary alcohol functional group, with the general structure HOC(R)(R') (R,R'=alkyl, aryl)." href="http://classyfire.wishartlab.com/tax_nodes/C0001661" rel="noopener" target="_blank">Secondary alcohols</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic compounds containing an heterocycle with at least one oxygen atom linked to a ring carbon." href="http://classyfire.wishartlab.com/tax_nodes/C0004140" rel="noopener" target="_blank">Oxacyclic compounds</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Compounds having the structure R2C(OR')2 ( R' not Hydrogen) and thus diethers of geminal diols. Originally, the term was confined to derivatives of aldehydes (one R = H), but it now applies equally to derivatives of ketones (neither R = H ). Mixed acetals have different R' groups." href="http://classyfire.wishartlab.com/tax_nodes/C0001656" rel="noopener" target="_blank">Acetals</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Carboxylic acids containing exactly one carboxyl groups." href="http://classyfire.wishartlab.com/tax_nodes/C0001137" rel="noopener" target="_blank">Monocarboxylic acids and derivatives</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic compounds containing an oxide group." href="http://classyfire.wishartlab.com/tax_nodes/C0003940" rel="noopener" target="_blank">Organic oxides</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Organic compounds containing a carbonyl group, with the general structure RC(=O)R', where R=organyl, R'=H, N, O, organyl group or halide group." href="http://classyfire.wishartlab.com/tax_nodes/C0001831" rel="noopener" target="_blank">Carbonyl compounds</a></span><span class="list-separator"> / </span><span class="separated-list-item"><a class="classyfire-taxnode" data-content="Derivatives of hydrocarbons obtained by substituting one or more carbon atoms by an heteroatom. They contain at least one carbon atom and heteroatom." href="http://classyfire.wishartlab.com/tax_nodes/C0004150" rel="noopener" target="_blank">Hydrocarbon derivatives</a></span></span></span></span><a class="taxonomy-toggler" href="javascript:void();"><div class="drugbank-icon icon-expand"><svg class="icon" role="img" title="expand">
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</div> show 14 more</a></dd><dt class="col-md-4 col-sm-5" id="substituents">Substituents</dt><dd class="col-md-8 col-sm-7"><span class="separated-list-container"><span class="separated-list col-lg-12 col-xl-6"><span class="separated-list-item">1,2-diol</span><span class="list-separator"> / </span><span class="separated-list-item">1-aryltetralin lignan</span><span class="list-separator"> / </span><span class="separated-list-item">Acetal</span><span class="list-separator"> / </span><span class="separated-list-item">Alcohol</span><span class="list-separator"> / </span><span class="separated-list-item">Alkyl aryl ether</span><span class="list-separator"> / </span><span class="separated-list-item">Anisole</span><span class="list-separator"> / </span><span class="separated-list-item">Aromatic heteropolycyclic compound</span><span class="list-separator"> / </span><span class="separated-list-item">Benzenoid</span><span class="list-separator"> / </span><span class="separated-list-item">Benzodioxole</span><span class="list-separator"> / </span><span class="separated-list-item">Carbonyl group</span></span></span><span class="hidden-taxonomy" style="display: none"><span class="list-separator"> / </span><span class="separated-list-container"><span class="separated-list col-lg-12 col-xl-6"><span class="separated-list-item">Carboxylic acid derivative</span><span class="list-separator"> / </span><span class="separated-list-item">Carboxylic acid ester</span><span class="list-separator"> / </span><span class="separated-list-item">Dimethoxybenzene</span><span class="list-separator"> / </span><span class="separated-list-item">Ether</span><span class="list-separator"> / </span><span class="separated-list-item">Gamma butyrolactone</span><span class="list-separator"> / </span><span class="separated-list-item">Hydrocarbon derivative</span><span class="list-separator"> / </span><span class="separated-list-item">Lactone</span><span class="list-separator"> / </span><span class="separated-list-item">Linear furanonaphthodioxole</span><span class="list-separator"> / </span><span class="separated-list-item">M-dimethoxybenzene</span><span class="list-separator"> / </span><span class="separated-list-item">Meta-dioxane</span><span class="list-separator"> / </span><span class="separated-list-item">Methoxybenzene</span><span class="list-separator"> / </span><span class="separated-list-item">Methoxyphenol</span><span class="list-separator"> / </span><span class="separated-list-item">Monocarboxylic acid or derivatives</span><span class="list-separator"> / </span><span class="separated-list-item">Monocyclic benzene moiety</span><span class="list-separator"> / </span><span class="separated-list-item">Monosaccharide</span><span class="list-separator"> / </span><span class="separated-list-item">Naphthofuran</span><span class="list-separator"> / </span><span class="separated-list-item">Organic oxide</span><span class="list-separator"> / </span><span class="separated-list-item">Organic oxygen compound</span><span class="list-separator"> / </span><span class="separated-list-item">Organoheterocyclic compound</span><span class="list-separator"> / </span><span class="separated-list-item">Organooxygen compound</span><span class="list-separator"> / </span><span class="separated-list-item">Oxacycle</span><span class="list-separator"> / </span><span class="separated-list-item">Oxane</span><span class="list-separator"> / </span><span class="separated-list-item">Phenol</span><span class="list-separator"> / </span><span class="separated-list-item">Phenol ether</span><span class="list-separator"> / </span><span class="separated-list-item">Phenoxy compound</span><span class="list-separator"> / </span><span class="separated-list-item">Podophyllotoxin</span><span class="list-separator"> / </span><span class="separated-list-item">Pyranodioxin</span><span class="list-separator"> / </span><span class="separated-list-item">Secondary alcohol</span><span class="list-separator"> / </span><span class="separated-list-item">Tetrahydrofuran</span><span class="list-separator"> / </span><span class="separated-list-item">Tetralin</span></span></span></span><a class="taxonomy-toggler" href="javascript:void();"><div class="drugbank-icon icon-expand"><svg class="icon" role="img" title="expand">
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</div> show 30 more</a></dd><dt class="col-md-4 col-sm-5" id="molecular-framework">Molecular Framework</dt><dd class="col-md-8 col-sm-7">Aromatic heteropolycyclic compounds</dd><dt class="col-md-4 col-sm-5" id="external-descriptors">External Descriptors</dt><dd class="col-md-8 col-sm-7"><span class="inline-separated-list-container"><span class="simple-separated-list-item">organic heterotetracyclic compound, beta-D-glucoside, furonaphthodioxole (<a href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:4911" rel="noopener" target="_blank">CHEBI:4911</a>) </span></span></dd></dl>