<p>Two cases of human overdoses with cysteamine are recorded in the literature, according to prescribing information. In one case, vomiting was immediate after the administration of cysteamine, and the patient did not experience other symptoms. A 200 to 250 mg/kg dose was accidentally ingested by a healthy 13-month-old child. Vomiting and dehydration followed. A full recovery was made after hospitalization and the replenishment of fluids.<sup class="text-reference-group"><a class="reference-popover-link" data-content="FDA Approved Products: CYSTAGON® (cysteamine bitartrate) oral capsules" href="#reference-L15646">13</a></sup></p><p>There is no known antidote for an overdose with cysteamine. In the case of an overdose, provide supportive treatment, especially to the cardiovascular and respiratory systems. Hemodialysis may be useful in some cases due to the fact that cysteamine has poor plasma protein binding.<sup class="text-reference-group"><a class="reference-popover-link" data-content="FDA Approved Products: CYSTAGON® (cysteamine bitartrate) oral capsules" href="#reference-L15646">13</a></sup></p>